pmxTools: Pharmacometric and Pharmacokinetic Toolkit
Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) <http://lixoft.com/wp-content/uploads/2016/03/PKPDlibrary.pdf>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).
| Version: | 1.3 |
| Depends: | R (≥ 3.50), patchwork |
| Imports: | ggplot2, chron, xml2, dplyr (≥ 0.8.5), tibble, gghalves, ggdist, scales, MASS, stringr, PKNCA, magrittr, data.tree |
| Suggests: | testthat, vdiffr, knitr, rmarkdown |
| Published: | 2023-02-21 |
| DOI: | 10.32614/CRAN.package.pmxTools |
| Author: | Justin Wilkins 
[aut, cre],
Bill Denney [aut],
Rik Schoemaker [aut],
Satyaprakash Nayak [ctb],
Leonid Gibiansky [ctb],
Andrew Hooker [ctb],
E. Niclas Jonsson [ctb],
Mats O. Karlsson [ctb],
John Johnson [ctb] |
| Maintainer: | Justin Wilkins <justin.wilkins at occams.com> |
| Contact: | Justin Wilkins <justin.wilkins@occams.com> |
| BugReports: | https://github.com/kestrel99/pmxTools/issues |
| License: | GPL-2 |
| URL: | https://github.com/kestrel99/pmxTools |
| NeedsCompilation: | no |
| Materials: | README NEWS |
| In views: | Pharmacokinetics |
| CRAN checks: | pmxTools results |
Documentation:
| Reference manual: | pmxTools.pdf |
| Vignettes: |
Drawing PK curves with pmxTools |
Downloads:
| Package source: | pmxTools_1.3.tar.gz |
| Windows binaries: | r-devel: pmxTools_1.3.zip, r-release: pmxTools_1.3.zip, r-oldrel: pmxTools_1.3.zip |
| macOS binaries: | r-devel (arm64): pmxTools_1.3.tgz, r-release (arm64): pmxTools_1.3.tgz, r-oldrel (arm64): pmxTools_1.3.tgz, r-devel (x86_64): pmxTools_1.3.tgz, r-release (x86_64): pmxTools_1.3.tgz, r-oldrel (x86_64): pmxTools_1.3.tgz |
| Old sources: | pmxTools archive |
Reverse dependencies:
| Reverse suggests: | mrgsolve, PKNCA |
Linking:
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