grandR 0.2.2

This is the release of grandR including improvements for the submission of the grand-Correct preprint

Major updates

• Enable simulation with non-constant rates
• 4sU dropout plots and grand-Correct functionality

Smaller updates

• Fixed a bug that caused warning messages after loading files.

grandR 0.2.1

This is the release of grandR including improvements for the revised version of the manuscript.

Major updates

• Enabled interface with Seurat
• Implemented estimation for pulse-chase experiments
• New vignettes for single cell data and pulse-chase data
• 4sU dropout plots
• Highlighting genes in the shiny web interface
• Cheatsheet

Smaller updates

• Compute BIC values for a list of models per gene and save it as an analysis table
• Additional parameters to PlotScatter
• Updated all calls to aes_string by tidy evaluation (for ggplot2 3.0 compatibility)
• Semantics for concentration fields
• Fixed issues when merging two data sets that were independently processed and have gene name dublettes
• FitKineticsGeneNtr now also computes residuals

grandR 0.2.0

This is the first release of grandR.

Available functionality

• Functions for loading GRAND-SLAM data
• Function for preprocessing
• Functions for kinetic modeling of progressive labeling time courses
• Functions to infer synthesis and half-lives from snapshot data
• Many helper functions (plotting, read simulation, etc.)
• Web-interface via shiny