Changes in version 1.0.0 (2019-12-01) + The first release of MAnorm2. + Uploaded to GitHub. Changes in version 1.1.0 (2021-04-18) + Add an option of using a pseudo-reference profile as baseline when performing normalization. + Implement a robust parameter estimation method that is based on Winsorization. + Implement the HyperChIP method for hypervariable ChIP-seq analysis. Changes in version 1.2.0 (2021-09-10) + Add the citation of HyperChIP. + Uploaded to the CRAN repository. Changes in version 1.2.1 (2022-08-24) + Update the citation of HyperChIP. + Fix some math rendering problems in HTML manuals. Changes in version 1.2.2 (2022-10-28) + Allow p_low and p_up to be larger than 0.5 in the Winsorization framework, as long as their sum is strictly smaller than 1.