DisHet: Estimate the Gene Expression Levels and Component Proportions of the Normal, Stroma (Immune) and Tumor Components of Bulk Tumor Samples

Model cell type heterogeneity of bulk renal cell carcinoma. The observed gene expression in bulk tumor sample is modeled by a log-normal distribution with the location parameter structured as a linear combination of the component-specific gene expressions.

Version: 1.0.0
Depends: R (≥ 2.15.0), gtools, matrixStats
Published: 2018-05-25
Author: Tao Wang
Maintainer: Tao Wang <tao.wang at utsouthwestern.edu>
License: GPL-2
NeedsCompilation: no
Materials: NEWS
CRAN checks: DisHet results

Documentation:

Reference manual: DisHet.pdf

Downloads:

Package source: DisHet_1.0.0.tar.gz
Windows binaries: r-devel: DisHet_1.0.0.zip, r-release: DisHet_1.0.0.zip, r-oldrel: DisHet_1.0.0.zip
macOS binaries: r-release (arm64): DisHet_1.0.0.tgz, r-oldrel (arm64): DisHet_1.0.0.tgz, r-release (x86_64): DisHet_1.0.0.tgz
Old sources: DisHet archive

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